Approximately half of the world’s population is at the risk of at least one vector-borne parasitic disease. The survival of intermediate hosts of vector-borne parasitic diseases is governed by various environmental factors, and remote sensing can be used to characterize and monitor environmental factors related to intermediate host breeding and reproduction, and become a powerful means to monitor the vector-borne parasitic diseases. In this research, satellite remotely sensed data has been used to obtain the environmental factors (vegetation, soil, temperature, terrain et al.), which are related to the living, multiplying and transmission of intermediate host. Then based on ground truth data, the remote sensing monitoring model of the intermediate host has been developed, which can enhance the remote sensing monitoring capabilities of the vector-borne parasitic disease and provide the theoretical foundation and technical support for diseases prevention and control.